Concept
Version 6
Created by Boundless
Types of Receptors
G-proteins
Heterotrimeric G proteins have three subunits: α, β, and γ. When a signaling molecule binds to a G-protein-coupled receptor in the plasma membrane, a GDP molecule associated with the α subunit is exchanged for GTP. The β and γ subunits dissociate from the α subunit, and a cellular response is triggered either by the α subunit or the dissociated β pair. Hydrolysis of GTP to GDP terminates the signal.
Source
Boundless vets and curates high-quality, openly licensed content from around the Internet. This particular resource used the following sources:
"OpenStax College, Signaling Molecules and Cellular Receptors. October 16, 2013."
http://cnx.org/content/m44451/latest/Figure_09_01_05.jpg
OpenStax CNX
CC BY 3.0.