In many land animals, it is the main end product of the metabolism of nitrogen-containing compounds, and is excreted in the urine.
Animals produce urea in the urea cycle, as it is a safe way to get rid of excess nitrogen.
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It is also a component of many fertilisers, providing a nitrogen source that is necessary for plants.
other uses besides to be added
The most common cause of hyperuricaemia is renal problems. It is measured along with creatinine to indicate direct problems with the kidneys (e.g. chronic renal failure[?]) or secondary problems such as hypothyroidism.
Urea levels can also be increased in some malignant blood disorders, (e.g. leukaemia and multiple myeloma[?]). There are also rare inherited metabolic defects[?] that can cause hyperuricaemia.
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