Proton pump inhibitors is a group of
drugs whose main action is pronounced and long-lasting reduction of
gastric acid[?] production. The group followed another group of
pharmaceuticals with similar action called
H2 antagonists[?].
Proton pump inhibitors act by by blocking the
hydrogen-
potassium adenosine triphosphatase[?] enzyme system (the so called
proton pump ) of the gastric
parietal cell[?]. Hence the enzyme inhibited is the terminal stage in gastric acid production. These drugs are utilized in treatment of :
Examples :