A
phospholipase is ...
(human cytosolic phospholipase A2:
PDB 1CJY (
http://www.rcsb.org/pdb/cgi/explore.cgi?pid=258171034362047&page=20&pdbId=1CJY), EC 3.1.1.4)
(
Bacillus Cereus:
PDB 1AH7 (
http://www.rcsb.org/pdb/cgi/explore.cgi?pid=266091034362355&page=0&pdbId=1AH7), EC 3.1.4.3)
Phospholipase C is a key
enzyme in phosphatidyl inositol
metabolism. It is activated by either
G proteins (making it part of a
G protein-coupled receptor signal transduction pathway) or by
transmembrane receptors with intrinsic or associated
tyrosine kinase activity. It converts
phosphatidyl inositol[?] to either
inositol triphosphate or
diacylglycerol.