Michael Smith (1932-2000) was the
1993 Nobel Prize winner in
Chemistry. He received the prize for his fundamental contributions to the establishment of
oligonucleotide-based, site-directed
mutagenesis and its development for
protein studies. Born in
Blackpool,
England, he worked out of the
University of British Columbia in
Vancouver,
Canada from
1956 until his death in
2000.