Güstrow is a Kreis (district) in central Mecklenburg-Western Pomerania, Germany. Area 2058 km², population 111,300 (2001). The district's capital is Güstrow.
This district is situated in the centre of Mecklenburg-Western Pomerania. The Warnow river runs through the district from the southwest to the north. In the southern part of the district there are several lakes constituting the northern edge of the Müritz lakeland.
From 1621 to 1695 the present-day district was occupied by the small duchy of Mecklenburg-Güstrow. Afterwards large parts belonged to the duchy of Mecklenburg-Schwerin, a small portion to the duchy of Mecklenburg-Strelitz (see Mecklenburg).
The district of Güstrow was established in 1994 by merging the former districts of Güstrow, Teterow and Bützow.
Towns in the district: Güstrow, Bützow[?], Teterow[?], Laage[?], Gnoien[?], Krakow[?].